Kemfor

Predict.
Explain.
Design.

The only platform that predicts chemical toxicity across 13,561 species, explains why using genomics, and generates new molecules for selective crop protection.

The Problem

The crop protection industry is broken.

$280M

Cost per molecule

12 years and $280 million per new agrochemical. No new herbicide mode of action in 35 years. 600+ resistant pest species.

5+

Siloed databases

Ecotoxicology data scattered across ECOTOX, ToxCast, CompTox, PubChem, and Ensembl. Assembling one dossier takes days.

<10

Species in published models

Published QSAR models cover fewer than 10 species and contain no genomic context. Kemfor covers 13,561.

$220 billion in annual crop losses from pests and disease. 40% of global crops lost annually. (UN FAO)

The Platform

Three layers. One decision.

Data Foundation

Ag Sensitivity Atlas

A normalized ecotoxicology and genomics dataset assembled for crop protection. Six source databases ingested, deduplicated, and standardized into a single queryable layer.

ECOTOX~1.2M chemical-species measurements from EPA/USGS
ToxCast2.78M in vitro bioactivity endpoints from EPA high-throughput assays
CompToxChemical safety dashboard — structure, physicochemical, hazard
PubChemBioactivity, structure, computed properties from NIH
Ensembl22,069 pesticide target genes across 122 species with transcriptomes
Scale28,355 compounds in atlas · 16,836 (59%) fully harmonized with CAS, InChIKey, SMILES

Live Platform

A prediction, in practice.

KemBoost evaluates any compound against 13,561 species in seconds — with gene-level attribution for the 378 species that have reference genomes.

platform.kemfor.ai/kemboost/predict
Kemfor
AtlasKemBoostKemGenOrchardMolecules
PREDICT
CompoundImidaclopridCAS 138261-41-3
SpeciesPredicted LC50RiskToxicity
Flour Beetle
0.0004 mg/LTARGET
100%
Honeybee
0.019 μg/beeMODERATE
36%
Daphnia magna
0.28 mg/LLOW
18%
Rainbow Trout
84.2 mg/LSAFE
4%
Corn (Zea mays)
71.3 mg/LSAFE
5%
Human
>450 mg/LSAFE
1%

Gene Attribution · Top Contributors

nAChR α60.891
CYP6G10.723
Rdl0.445
+ 22,066 more genes evaluated
0Compoundsmolecules16,836 with SMILES + InChIKey
0Speciesorganisms378 with reference genome
0Measurementsdata points2.78M ToxCast HTS bioactivity
0Target Genesgenomic122 species with transcriptome

KemGen

182x

pest-vs-crop selectivity

KemGen generates novel molecules scored across 7 dimensions: pest LC50, crop LC50, bee safety, human dietary safety, QED synthesizability, Tox21 flags, and composite selectivity index.

Selectivity Index

Pest LC50 ÷ Crop LC50 ratio per generated molecule

×
Cornvs. Flour Beetle
182x
Top result
Tomatovs. Bollworm
36x
Ricevs. Armyworm
18x
Soybeanvs. Aphid
16x
Cabbagevs. Diamond Moth
10x
0x50x100x150x182x

Who We Serve

Built for the teams doing the work.

Regulatory Consultants

Replace days of manual data reconciliation with a single query. Toxicity landscapes, data gap analysis, and read-across justification for PMRA/EPA submissions.

CRO Ecotoxicology Teams

Know what data exists before you design a study. Pre-study coverage assessments that save budget and shorten timelines.

Agrochemical R&D

KemGen generates novel molecules scored across 7 dimensions: pest LC50, crop LC50, bee safety, human dietary safety, QED synthesizability, Tox21 flags, and selectivity index.

Crop Advisors

Seasonal threat intelligence linked to active ingredient data and full ecotoxicological profiles for every product.

Get Started

Ready to see the platform?

We're happy to walk you through the platform and discuss how Kemfor fits your workflow.

Location

Toronto, Canada